Methylation Dynamics of <i>RASSF1A</i> and Its Impact on Cancer

5-methyl cytosine (5mC) is a key epigenetic mark entwined with gene expression and the specification of cellular phenotypes. Its distribution around gene promoters sets a barrier for transcriptional enhancers or inhibitor proteins binding to their target sequences. As a result, an additional level o...

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Bibliographic Details
Main Authors: Giorgio Malpeli, Giulio Innamorati, Ilaria Decimo, Maria Bencivenga, Armel Herve Nwabo Kamdje, Roberto Perris, Claudio Bassi
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/7/959