Endothelial Shear Stress and Platelet FcγRIIa Expression in Intracranial Atherosclerotic Disease

Endothelial Shear Stress and Platelet FcγRIIa Expression in Intracranial Atherosclerotic Disease

Intracranial atherosclerotic disease (ICAD) has been characterized by the degree of arterial stenosis and downstream hypoperfusion, yet microscopic derangements of endothelial shear stress at the luminal wall may be key determinants of plaque growth, vascular remodeling and thrombosis that culminate...

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Bibliographic Details
Main Authors: David S. Liebeskind, Jason D. Hinman, Naoki Kaneko, Hiroaki Kitajima, Tristan Honda, Adam H. De Havenon, Edward Feldmann, Raul G. Nogueira, Shyam Prabhakaran, Jose G. Romano, Peter W. Callas, David J. Schneider
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Neurology
Subjects:
intracranial atherosclerosis
stroke
shear stress
FcγRIIa receptor
platelet activation and reactivity
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.646309/full

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https://www.frontiersin.org/articles/10.3389/fneur.2021.646309/full

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