CircDLST promotes the tumorigenesis and metastasis of gastric cancer by sponging miR-502-5p and activating the NRAS/MEK1/ERK1/2 signaling

CircDLST promotes the tumorigenesis and metastasis of gastric cancer by sponging miR-502-5p and activating the NRAS/MEK1/ERK1/2 signaling

Abstract Background Accumulating evidence shows that, the dysregulation of circular RNAs (circRNAs) is associated with the progression of multiple malignancies. But, the underlying mechanisms by which has_circ_0032627 (circDLST) contributed to gastric cancer (GC) remain undocumented. Methods The exp...

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Bibliographic Details
Main Authors: Jing Zhang, Lidan Hou, Rui Liang, Xiaoyu Chen, Rui Zhang, Wei Chen, Jinshui Zhu
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Molecular Cancer
Subjects:
circDLST
miR-502-5p
NRAS
Growth
Metastasis
Gastric cancer
Online Access:http://link.springer.com/article/10.1186/s12943-019-1015-1

Internet

http://link.springer.com/article/10.1186/s12943-019-1015-1

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