Annexin A1 Is Required for Efficient Tumor Initiation and Cancer Stem Cell Maintenance in a Model of Human Breast Cancer

Annexin A1 Is Required for Efficient Tumor Initiation and Cancer Stem Cell Maintenance in a Model of Human Breast Cancer

Triple-negative breast cancer (TNBC) has a poor outcome compared to other breast cancer subtypes, and new therapies that target the molecular alterations driving tumor progression are needed. Annexin A1 is an abundant multi-functional Ca<sup>2+</sup> binding and membrane-associated prote...

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Bibliographic Details
Main Authors: Cameron N. Johnstone, Yan Tu, Shenna Langenbach, David Baloyan, Andrew D. Pattison, Peter Lock, Kara L. Britt, Brian D. Lehmann, Traude H. Beilharz, Matthias Ernst, Robin L. Anderson, Alastair G. Stewart
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
Annexin A1
breast cancer
mouse model
allograft
xenograft
Online Access:https://www.mdpi.com/2072-6694/13/5/1154

Internet

https://www.mdpi.com/2072-6694/13/5/1154

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