The 3D8 single chain variable fragment protein suppresses Newcastle disease virus transmission in transgenic chickens

The 3D8 single chain variable fragment protein suppresses Newcastle disease virus transmission in transgenic chickens

Abstract Background The 3D8 single chain variable fragment (scFv) is a mini-antibody sequence that exhibits independent nuclease activity against all types of nucleic acids. In this research, crossing a 3D8 scFv G1 transgenic rooster with wild-type hens produced 3D8 scFv G2 transgenic chickens to ev...

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Bibliographic Details
Main Authors: Sung June Byun, Hoonsung Choi, Shanmugam Sureshkumar, Seong-Su Yuk, Jung-Hoon Kwon, Jin-Yong Noh, Sun Keun Jung, Jeom Sun Kim, Keon Bong Oh, Hyeon Yang, Gunsup Lee, Hwi-Cheul Lee, Jae-Seok Woo, Chang-Seon Song
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Veterinary Research
Subjects:
Newcastle disease virus (NDV)
3D8 ScFv
chicken
transgenic
Online Access:http://link.springer.com/article/10.1186/s12917-020-02462-9

Internet

http://link.springer.com/article/10.1186/s12917-020-02462-9

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