Butyric Acid Increases the Therapeutic Effect of EHLJ7 on Ulcerative Colitis by Inhibiting JAK2/STAT3/SOCS1 Signaling Pathway

Butyric Acid Increases the Therapeutic Effect of EHLJ7 on Ulcerative Colitis by Inhibiting JAK2/STAT3/SOCS1 Signaling Pathway

Ulcerative colitis (UC) is a refractory chronic disease characterized by bloody diarrhea and mucosal or submucosal ulcers. There is an urgent need of new drugs for the treatment of ulcerative colitis. EHLJ7 is a quaternary coptisine derivative. Herein, we explored the therapeutic effect of EHLJ7 on...

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Bibliographic Details
Main Authors: Xiaonan Tang, Xiang Li, Yufei Wang, ZhiHui Zhang, AnJun Deng, WenJie Wang, Haijing Zhang, Hailin Qin, LianQiu Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Pharmacology
Subjects:
ulcerative colitis
butyric acid
JAK2
STAT3
SOCS1
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01553/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01553/full

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