Circulating matrix metalloproteinases are associated with arterial stiffness in patients with type 1 diabetes: pooled analysis of three cohort studies

Circulating matrix metalloproteinases are associated with arterial stiffness in patients with type 1 diabetes: pooled analysis of three cohort studies

Abstract Background Altered regulation of extracellular matrix (ECM) composition by matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase (TIMPs) may contribute to arterial stiffening. We investigated associations between circulating MMP-1, -2, -3, -9, -10 and TIMP-1, and carot...

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Main Authors: Stijn A. Peeters, Lian Engelen, Jacqueline Buijs, Nish Chaturvedi, John H. Fuller, Anders Jorsal, Hans-Henrik Parving, Lise Tarnow, Simone Theilade, Peter Rossing, Casper G. Schalkwijk, Coen D. A. Stehouwer
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Cardiovascular Diabetology
Subjects:
Type 1 diabetes
Matrix metalloproteinase
Tissue inhibitor of metalloproteinase
Pulse pressure
Arterial stiffness
Carotid-femoral pulse wave velocity
Online Access:http://link.springer.com/article/10.1186/s12933-017-0620-9

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http://link.springer.com/article/10.1186/s12933-017-0620-9

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