Identification of the neogenin-binding site on the repulsive guidance molecule A.

Repulsive guidance molecule (RGM) is a membrane-bound protein that was originally identified as an axon guidance molecule in the chick retinotectal system. RGMa, one of the 3 isoforms found in mammals, is involved in laminar patterning, cephalic neural tube closure, axon guidance, and inhibition of...

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Bibliographic Details
Main Authors: Takahide Itokazu, Yuki Fujita, Ryosuke Takahashi, Toshihide Yamashita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3291610?pdf=render