A combination of genomic approaches reveals the role of FOXO1a in regulating an oxidative stress response pathway.

While many of the phenotypic differences between human and chimpanzee may result from changes in gene regulation, only a handful of functionally important regulatory differences are currently known. As a first step towards identifying transcriptional pathways that have been remodeled in the human li...

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Bibliographic Details
Main Authors: Paola de Candia, Ran Blekhman, Adrien E Chabot, Alicia Oshlack, Yoav Gilad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2244703?pdf=render