Hippocampal overexpression of Down syndrome cell adhesion molecule in amyloid precursor protein transgenic mice

Hippocampal overexpression of Down syndrome cell adhesion molecule in amyloid precursor protein transgenic mice

Down syndrome cell adhesion molecule (DSCAM) is located within the Down syndrome critical region of chromosome 21. DSCAM is a broadly expressed neurodevelopmental protein involved in synaptogenesis, neurite outgrowth, and axon guidance. We previously demonstrated DSCAM overexpression in the cortex o...

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Bibliographic Details
Main Authors: Y.L. Jia, Z.X. Fu, B.H. Zhang, Y.J. Jia
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Down syndrome cell adhesion molecule
Amyloid precursor protein
Transgenic mouse
Hippocampus
Dementia
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000600603&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000600603&lng=en&tlng=en

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