A comparison of epigenetic mitotic-like clocks for cancer risk prediction
Abstract Background DNA methylation changes that accrue in the stem cell pool of an adult tissue in line with the cumulative number of cell divisions may contribute to the observed variation in cancer risk among tissues and individuals. Thus, the construction of epigenetic “mitotic” clocks that can...
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| Format: | Article |
| Language: | English |
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BMC
2020-06-01
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| Series: | Genome Medicine |
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| Online Access: | http://link.springer.com/article/10.1186/s13073-020-00752-3 |