Altered nicotine reward-associated behavior following α4 nAChR subunit deletion in ventral midbrain.

Altered nicotine reward-associated behavior following α4 nAChR subunit deletion in ventral midbrain.

Nicotinic acetylcholine receptors containing α4 subunits (α4β2* nAChRs) are critical for nicotinic cholinergic transmission and the addictive action of nicotine. To identify specific activities of these receptors in the adult mouse brain, we coupled targeted deletion of α4 nAChR subunits with behavi...

Full description

Bibliographic Details
Main Authors: Can Peng, Staci E Engle, Yijin Yan, Marcus M Weera, Jennifer N Berry, Matthew C Arvin, Guiqing Zhao, J Michael McIntosh, Julia A Chester, Ryan M Drenan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5536316?pdf=render

Internet

http://europepmc.org/articles/PMC5536316?pdf=render

Similar Items