Warfarin maintenance dose prediction for Chinese after heart valve replacement by a feedforward neural network with equal stratified sampling

Abstract Patients requiring low-dose warfarin are more likely to suffer bleeding due to overdose. The goal of this work is to improve the feedforward neural network model's precision in predicting the low maintenance dose for Chinese in the aspect of training data construction. We built the mod...

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Bibliographic Details
Main Authors: Weijie Ma, Hongying Li, Li Dong, Qin Zhou, Bo Fu, Jiang-long Hou, Jing Wang, Wenzhe Qin, Jin Chen
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-93317-2