Clinical significance of long non-coding RNA HOTTIP in early-stage non-small-cell lung cancer

Abstract Background HOTTIP, a long non-coding RNA located in the HOXA cluster, plays a role in the patterning of tissues with mesodermal components, including the lung. Overexpression of HOXA genes, including HOTTIP, has been associated with a more aggressive phenotype in several cancers. However, t...

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Bibliographic Details
Main Authors: Alfons Navarro, Jorge Moises, Sandra Santasusagna, Ramon M. Marrades, Nuria Viñolas, Joan J. Castellano, Jordi Canals, Carmen Muñoz, José Ramírez, Laureano Molins, Mariano Monzo
Format: Article
Language:English
Published: BMC 2019-02-01
Series:BMC Pulmonary Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12890-019-0816-8