Skin electroporation: effects on transgene expression, DNA persistence and local tissue environment.

BACKGROUND: Electrical pulses have been used to enhance uptake of molecules into living cells for decades. This technique, often referred to as electroporation, has become an increasingly popular method to enhance in vivo DNA delivery for both gene therapy applications as well as for delivery of vac...

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Bibliographic Details
Main Authors: Anna-Karin Roos, Fredrik Eriksson, James A Timmons, Josefine Gerhardt, Ulrika Nyman, Lindvi Gudmundsdotter, Andreas Bråve, Britta Wahren, Pavel Pisa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2748717?pdf=render