Characterization of Type I Interferon-Associated Chemokines and Cytokines in Lacrimal Glands of Nonobese Diabetic Mice

Characterization of Type I Interferon-Associated Chemokines and Cytokines in Lacrimal Glands of Nonobese Diabetic Mice

Type I interferons (IFNs) are required for spontaneous lacrimal gland inflammation in the nonobese diabetic (NOD) mouse model of Sjögren’s disease, but the consequences of type I IFN signaling are not well-defined. Here, we use RNA sequencing to define cytokine and chemokine genes upregulated in lac...

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Bibliographic Details
Main Authors: Merri-Grace Allred, Michael S. Chimenti, Ashley E. Ciecko, Yi-Guang Chen, Scott M. Lieberman
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
Sjögren’s disease
lacrimal gland
nonobese diabetic mice
type I interferon
interleukin-21
chemokines
Online Access:https://www.mdpi.com/1422-0067/22/7/3767

Internet

https://www.mdpi.com/1422-0067/22/7/3767

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