A pyrazolyl-thiazole derivative causes antinociception in mice

A pyrazolyl-thiazole derivative causes antinociception in mice

The present study investigates the antinociceptive effect of the pyrazolyl-thiazole derivative 2-(5-trichloromethyl-5-hydroxy-3-phenyl-4,5-dihydro-1 H-pyrazol-1-yl)-4-(4-bromophenyl)-5-methylthiazole (B50) in mice. Male albino Swiss mice (30-40 g) were used in the acetic acid-induced abdominal writh...

Full description

Bibliographic Details
Main Authors: C.R. Prokopp, M.A. Rubin, P.D. Sauzem, A.H. de Souza, D.B. Berlese, R.V. Lourega, M.N. Muniz, H.G. Bonacorso, N. Zanatta, M.A.P. Martins, C.F. Mello
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2006-06-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Antinociception
Pyrazolyl-thiazole derivatives
Writhing test
Opioid mechanism
Naloxone
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000600013

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000600013

Similar Items