Activity of Plasmodium vivax promoter elements in Plasmodium knowlesi, and a centromere-containing plasmid that expresses NanoLuc throughout the parasite life cycle

Activity of Plasmodium vivax promoter elements in Plasmodium knowlesi, and a centromere-containing plasmid that expresses NanoLuc throughout the parasite life cycle

Abstract Background Plasmodium knowlesi is now the major cause of human malaria in Malaysia, complicating malaria control efforts that must attend to the elimination of multiple Plasmodium species. Recent advances in the cultivation of P. knowlesi erythrocytic-stage parasites in vitro, transformatio...

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Bibliographic Details
Main Authors: Roberto R. Moraes Barros, Kittisak Thawnashom, Tyler J. Gibson, Jennifer S. Armistead, Ramoncito L. Caleon, Miho Kaneko, Whitney A. Kite, J. Patrick Mershon, Jacqueline K. Brockhurst, Theresa Engels, Lynn Lambert, Sachy Orr-Gonzalez, John H. Adams, Juliana M. Sá, Osamu Kaneko, Thomas E. Wellems
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Malaria Journal
Subjects:
Heterologous transfection
Transgenic parasites
Genetic transformation
Luciferase expression
In vitro growth assays
Antimalarial drug response assays
Online Access:https://doi.org/10.1186/s12936-021-03773-4

Internet

https://doi.org/10.1186/s12936-021-03773-4

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