Using the half normal distribution to quantify covariate balance in cluster-randomized pragmatic trials

Abstract Background Pragmatic trials often consist of cluster-randomized controlled trials (C-RCTs), where staff of existing clinics or sites deliver interventions and randomization occurs at the site level. Covariate-constrained randomization (CCR) methods are often recommended to minimize imbalanc...

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Bibliographic Details
Main Authors: Jin Huang, David L. Roth
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-021-05122-x