The prefoldin bud27 mediates the assembly of the eukaryotic RNA polymerases in an rpb5-dependent manner.

The unconventional prefoldin URI/RMP, in humans, and its orthologue in yeast, Bud27, have been proposed to participate in the biogenesis of the RNA polymerases. However, this role of Bud27 has not been confirmed and is poorly elucidated. Our data help clarify the mechanisms governing biogenesis of t...

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Bibliographic Details
Main Authors: María Carmen Mirón-García, Ana Isabel Garrido-Godino, Varinia García-Molinero, Francisco Hernández-Torres, Susana Rodríguez-Navarro, Francisco Navarro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3573130?pdf=render