Characterizing the interplay between gene nucleotide composition bias and splicing

Characterizing the interplay between gene nucleotide composition bias and splicing

Abstract Background Nucleotide composition bias plays an important role in the 1D and 3D organization of the human genome. Here, we investigate the potential interplay between nucleotide composition bias and the regulation of exon recognition during splicing. Results By analyzing dozens of RNA-seq d...

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Bibliographic Details
Main Authors: Sébastien Lemaire, Nicolas Fontrodona, Fabien Aubé, Jean-Baptiste Claude, Hélène Polvèche, Laurent Modolo, Cyril F. Bourgeois, Franck Mortreux, Didier Auboeuf
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Genome Biology
Subjects:
Splicing
Genomic
Chromatin organization
Nucleotide composition bias
Online Access:https://doi.org/10.1186/s13059-019-1869-y

Internet

https://doi.org/10.1186/s13059-019-1869-y

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