Protein quantitative trait locus study in obesity during weight-loss identifies a leptin regulator

Protein quantitative trait locus study in obesity during weight-loss identifies a leptin regulator

Although many genetic variants are known for obesity, their function remains largely unknown. Here, in a weight-loss intervention cohort, the authors identify protein quantitative trait loci associated with BMI at baseline and after weight loss and find FAM46A to be a regulator of leptin in adipocyt...

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Bibliographic Details
Main Authors: Jérôme Carayol, Christian Chabert, Alessandro Di Cara, Claudia Armenise, Gregory Lefebvre, Dominique Langin, Nathalie Viguerie, Sylviane Metairon, Wim H. M. Saris, Arne Astrup, Patrick Descombes, Armand Valsesia, Jörg Hager
Format: Article
Language:English
Published: Nature Publishing Group 2017-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02182-z

Internet

https://doi.org/10.1038/s41467-017-02182-z

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