Xingnaojing ameliorates synaptic plasticity and memory deficits in an Aβ1–42 induced mouse model of Alzheimer's disease

Xingnaojing ameliorates synaptic plasticity and memory deficits in an Aβ1–42 induced mouse model of Alzheimer's disease

The accumulation of insoluble amyloid β (Aβ) peptides is one of the pathological changes in Alzheimer's disease (AD), which induced synaptic plasticity impairment and excitatory amino acid toxicity associated with decreased memory function. Xingnaojing (XNJ), a well-known prescription in tradit...

Full description

Bibliographic Details
Main Authors: Yi Liu, Siyi Xu, Huijie Bian, Yi Qian, Huiya Li, Shu Shu, Jiang Chen, Xiang Cao, Yue Gu, Jiali Jin, Xi Zhang, Yun Xu, Xiaolei Zhu
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Journal of Pharmacological Sciences
Subjects:
Alzheimer's disease
Amyloid-β
Synaptic plasticity
NMDAR
Xingnaojing
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861320300463

Internet

http://www.sciencedirect.com/science/article/pii/S1347861320300463

Similar Items