Knockdown of microsomal glutathione S-transferase 1 inhibits lung adenocarcinoma cell proliferation and induces apoptosis

Knockdown of microsomal glutathione S-transferase 1 inhibits lung adenocarcinoma cell proliferation and induces apoptosis

Background: Lung cancer has been the most common cancer worldwide. Microsomal glutathione S-transferase 1 (MGST1) has been reported to play vital roles in oxidative stress, tumor occurrence and drug resistance. However, the biological function and molecular mechanism of MGST1 in lung adenocarcinoma...

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Bibliographic Details
Main Authors: Baozhen Zeng, Chunlei Ge, Ruilei Li, Zhiwei Zhang, Qiaofen Fu, Zhen Li, Zhuying Lin, Lin Liu, Yuanbo Xue, Yuanyuan Xu, Juan He, Huan Guo, Chunyan Li, Wenhua Huang, Xin Song, Youguang Huang
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Microsomal glutathione transferase-1
Lung adenocarcinoma
Proliferation
Apoptosis
AKT/GSK-3β
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219351856

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http://www.sciencedirect.com/science/article/pii/S0753332219351856

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