Linkage of type I interferon activity and TNF-alpha levels in serum with sarcoidosis manifestations and ancestry.

Linkage of type I interferon activity and TNF-alpha levels in serum with sarcoidosis manifestations and ancestry.

BACKGROUND: Both type I interferon (IFN), also known as IFN-α and tumor necrosis factor alpha (TNF-α) have been implicated in the pathogenesis of sarcoidosis. We investigated serum levels of these cytokines in a large multi-ancestral sarcoidosis population to determine correlations between cytokine...

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Bibliographic Details
Main Authors: Nadera J Sweiss, Wei Zhang, Beverly S Franek, Silvia N Kariuki, David R Moller, Karen C Patterson, Peggy Bennett, Lakshmi R Girijala, Vaisak Nair, Robert P Baughman, Joe G N Garcia, Timothy B Niewold
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3237595?pdf=render

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http://europepmc.org/articles/PMC3237595?pdf=render

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