Epigenetic profiles in children with a neural tube defect; a case-control study in two populations.

Epigenetic profiles in children with a neural tube defect; a case-control study in two populations.

Folate deficiency is implicated in the causation of neural tube defects (NTDs). The preventive effect of periconceptional folic acid supplement use is partially explained by the treatment of a deranged folate-dependent one carbon metabolism, which provides methyl groups for DNA-methylation as an epi...

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Bibliographic Details
Main Authors: Lisette Stolk, Marieke I Bouwland-Both, Nina H van Mil, Michael M P J Verbiest, Paul H C Eilers, Huiping Zhu, Lucina Suarez, André G Uitterlinden, Régine P M Steegers-Theunissen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3818348?pdf=render

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http://europepmc.org/articles/PMC3818348?pdf=render

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