Increasing Nucleosome Occupancy Is Correlated with an Increasing Mutation Rate so Long as DNA Repair Machinery Is Intact.

Increasing Nucleosome Occupancy Is Correlated with an Increasing Mutation Rate so Long as DNA Repair Machinery Is Intact.

Deciphering the multitude of epigenomic and genomic factors that influence the mutation rate is an area of great interest in modern biology. Recently, chromatin has been shown to play a part in this process. To elucidate this relationship further, we integrated our own ultra-deep sequenced human nuc...

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Bibliographic Details
Main Authors: Puya G Yazdi, Brian A Pedersen, Jared F Taylor, Omar S Khattab, Yu-Han Chen, Yumay Chen, Steven E Jacobsen, Ping H Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4550472?pdf=render

Internet

http://europepmc.org/articles/PMC4550472?pdf=render

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