Synthesis of Ribavirin, Tecadenoson, and Cladribine by Enzymatic Transglycosylation

Synthesis of Ribavirin, Tecadenoson, and Cladribine by Enzymatic Transglycosylation

Despite the impressive progress in nucleoside chemistry to date, the synthesis of nucleoside analogues is still a challenge. Chemoenzymatic synthesis has been proven to overcome most of the constraints of conventional nucleoside chemistry. A purine nucleoside phosphorylase from <i>Aeromonas hy...

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Bibliographic Details
Main Authors: Marco Rabuffetti, Teodora Bavaro, Riccardo Semproli, Giulia Cattaneo, Michela Massone, Carlo F. Morelli, Giovanna Speranza, Daniela Ubiali
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Catalysts
Subjects:
Ribavirin
Tecadenoson
Cladribine
purine nucleoside phosphorylase
transglycosylation reaction
7-methylguanosine iodide
7-methyl-2′-deoxyguanosine iodide
7-methylguanine arabinoside iodide
Online Access:https://www.mdpi.com/2073-4344/9/4/355

Internet

https://www.mdpi.com/2073-4344/9/4/355

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