The Interaction of Ile-Phe Dipeptide with Phosphatidylinositide 3-Kinase (PI3K): Molecular Dynamics and Molecular Docking Studies

Self-assembly of phenylalanine creates Phe fibers which is the characteristic fiber model found in amyloid fibrils linked with various neurodegenerative diseases. L-Isoleucyl-L-Phenylalanine (IlePhe) dipeptide is composed of isoleucine and phenylalanine amino acids, having fibrillary structure simil...

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Bibliographic Details
Main Authors: Bilge Bicak, Yagmur Kokcu, Serda Kecel-Gunduz, Aysen E. Ozel, Sevim Akyuz
Format: Article
Language:English
Published: Natural and Engineering Sciences 2020-02-01
Series:Natural and Engineering Sciences
Subjects:
Online Access:https://www.nesciences.com/download.php?id=431