Proteomic analyses reveal high expression of decorin and endoplasmin (HSP90B1) are associated with breast cancer metastasis and decreased survival.

Breast cancer is the most common malignancy among women worldwide in terms of incidence and mortality. About 10% of North American women will be diagnosed with breast cancer during their lifetime and 20% of those will die of the disease. Breast cancer is a heterogeneous disease and biomarkers able t...

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Main Authors: Thomas R Cawthorn, Juan C Moreno, Moyez Dharsee, Danh Tran-Thanh, Suzanne Ackloo, Pei Hong Zhu, Girish Sardana, Jian Chen, Peter Kupchak, Lindsay M Jacks, Naomi A Miller, Bruce J Youngson, Vladimir Iakovlev, Cynthia J Guidos, Katherine A Vallis, Kenneth R Evans, David McCready, Wey L Leong, Susan J Done
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3282708?pdf=render