Hypoxia inducible factor 2α (HIF2α/EPAS1) is associated with development of pulmonary hypertension in severe congenital diaphragmatic hernia patients

Hypoxia inducible factor 2α (HIF2α/EPAS1) is associated with development of pulmonary hypertension in severe congenital diaphragmatic hernia patients

We show that hypoxia inducible factor 2α (HIF2α) is highly expressed in patients with pulmonary hypertension (PH). HIF2α is expressed in every patient with congenital diaphragmatic hernia, while only half of the controls express HIF2α. Our data suggest that HIF2α is a link between hypoxia and the de...

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Bibliographic Details
Main Authors: Yadi Huang, Anne Boerema-de Munck, Marjon Buscop-van Kempen, Ilona Sluiter, Ronald de Krijger, Dick Tibboel, Robbert J. Rottier
Format: Article
Language:English
Published: SAGE Publishing 2018-06-01
Series:Pulmonary Circulation
Online Access:https://doi.org/10.1177/2045894018783734

Internet

https://doi.org/10.1177/2045894018783734

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