Arete – candidate gene prioritization using biological network topology with additional evidence types

Arete – candidate gene prioritization using biological network topology with additional evidence types

Abstract Background Refinement of candidate gene lists to select the most promising candidates for further experimental verification remains an essential step between high-throughput exploratory analysis and the discovery of specific causal genes. Given the qualitative and semantic complexity of bio...

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Bibliographic Details
Main Authors: Artem Lysenko, Keith Anthony Boroevich, Tatsuhiko Tsunoda
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BioData Mining
Subjects:
Gene prioritisation
Biological network analysis
Cytoscape
Random walk
DIAMOnD
Online Access:http://link.springer.com/article/10.1186/s13040-017-0141-9

Internet

http://link.springer.com/article/10.1186/s13040-017-0141-9

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