Development of a Microfluidic-Based Optical Sensing Device for Label-Free Detection of Circulating Tumor Cells (CTCs) Through Their Lactic Acid Metabolism

Development of a Microfluidic-Based Optical Sensing Device for Label-Free Detection of Circulating Tumor Cells (CTCs) Through Their Lactic Acid Metabolism

This study reports a microfluidic-based optical sensing device for label-free detection of circulating tumor cells (CTCs), a rare cell species in blood circulation. Based on the metabolic features of cancer cells, live CTCs can be quantified indirectly through their lactic acid production. Compared...

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Bibliographic Details
Main Authors: Tzu-Keng Chiu, Kin-Fong Lei, Chia-Hsun Hsieh, Hung-Bo Hsiao, Hung-Ming Wang, Min-Hsien Wu
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Sensors
Subjects:
microfluidic technology
optical sensing
circulating tumor cells (CTCs)
cancer cells
lactic acid
Online Access:http://www.mdpi.com/1424-8220/15/3/6789

Internet

http://www.mdpi.com/1424-8220/15/3/6789

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