Activation of the IL-2 Receptor in Podocytes: A Potential Mechanism for Podocyte Injury in Idiopathic Nephrotic Syndrome?

Activation of the IL-2 Receptor in Podocytes: A Potential Mechanism for Podocyte Injury in Idiopathic Nephrotic Syndrome?

The renal podocyte plays an important role in maintaining the structural integrity of the glomerular basement membrane. We have previously reported that patients with idiopathic nephrotic syndrome (INS) have increased IL-2 production. We hypothesized that podocytes express an IL-2 receptor (IL-2R) a...

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Bibliographic Details
Main Authors: Arnold H Zea, Tyrus Stewart, Jeannine Ascani, David J Tate, Beatriz Finkel-Jimenez, Anna Wilk, Krzysztof Reiss, William E Smoyer, Diego H Aviles
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4936730?pdf=render

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http://europepmc.org/articles/PMC4936730?pdf=render

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