Diminished expression of major histocompatibility complex facilitates the use of human induced pluripotent stem cells in monkey

Diminished expression of major histocompatibility complex facilitates the use of human induced pluripotent stem cells in monkey

Abstract Background Stem cells, including induced pluripotent stem cells (iPSCs), have tremendous potential in health care, though with several significant limitations. Each of the limitations, including immunogenicity, may block most of the therapeutic potentials. Beta2 microglobulin (B2M) and MHC...

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Bibliographic Details
Main Authors: Xiaokai Wang, Meng Lu, Xiaoyu Tian, Yansong Ren, Yijun Li, Meng Xiang, Sifeng Chen
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Stem Cell Research & Therapy
Subjects:
Induced pluripotent stem cells
Major histocompatibility complex
Stem cell immunogenicity
Non-human primate
Wound healing
Online Access:http://link.springer.com/article/10.1186/s13287-020-01847-9

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http://link.springer.com/article/10.1186/s13287-020-01847-9

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