The Mammalian "Obesogen" Tributyltin Targets Hepatic Triglyceride Accumulation and the Transcriptional Regulation of Lipid Metabolism in the Liver and Brain of Zebrafish.

The Mammalian "Obesogen" Tributyltin Targets Hepatic Triglyceride Accumulation and the Transcriptional Regulation of Lipid Metabolism in the Liver and Brain of Zebrafish.

Recent findings indicate that different Endocrine Disrupting Chemicals (EDCs) interfere with lipid metabolic pathways in mammals and promote fat accumulation, a previously unknown site of action for these compounds. The antifoulant and environmental pollutant tributyltin (TBT), which causes imposex...

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Bibliographic Details
Main Authors: Angeliki Lyssimachou, Joana G Santos, Ana André, Joana Soares, Daniela Lima, Laura Guimarães, C Marisa R Almeida, Catarina Teixeira, L Filipe C Castro, Miguel M Santos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4669123?pdf=render

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http://europepmc.org/articles/PMC4669123?pdf=render

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