HMGB1 Promotes Myeloid Egress and Limits Lymphatic Clearance of Malignant Pleural Effusions

HMGB1 Promotes Myeloid Egress and Limits Lymphatic Clearance of Malignant Pleural Effusions

Pleural effusions, when benign, are attributed to cardiac events and suffusion of fluid within the pleural space. When malignant, lymphatic obstruction by tumor and failure to absorb constitutively produced fluid is the predominant formulation. The prevailing view has been challenged recently, namel...

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Bibliographic Details
Main Authors: Adam C. Soloff, Katherine E. Jones, Amy A. Powers, Pranav Murthy, Yue Wang, Kira L. Russell, Miranda Byrne-Steele, Amanda W. Lund, Jian-Min Yuan, Sara E. Monaco, Jian Han, Rajeev Dhupar, Michael T. Lotze
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
HMGB1
malignant pleural effusions
benign pleural effusions
immune repertoire
tumor immunology
γδ T cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.02027/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.02027/full

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