Apoptosis inducing effect of plumbagin on colonic cancer cells depends on expression of COX-2.

Apoptosis inducing effect of plumbagin on colonic cancer cells depends on expression of COX-2.

Plumbagin, a quinonoid found in the plants of the Plumbaginaceae, possesses medicinal properties. In this study we investigated the anti-proliferative and apoptotic activity of plumbagin by using two human colonic cancer cell lines, HT29 and HCT15. IC50 of Plumbagin for HCT15 and HT29 cells (22.5 µM...

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Main Authors: Bharathi Raja Subramaniya, Gayathri Srinivasan, Sakeena Sadullah Mohammed Sadullah, Nimitha Davis, Lakshmi Baddi Reddi Subhadara, Devaraj Halagowder, Niranjali Devaraj Sivasitambaram
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21559086/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21559086/?tool=EBI

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