Coupling of Cell Surface Biotinylation and SILAC-Based Quantitative Proteomics Identified Myoferlin as a Potential Therapeutic Target for Nasopharyngeal Carcinoma Metastasis

Coupling of Cell Surface Biotinylation and SILAC-Based Quantitative Proteomics Identified Myoferlin as a Potential Therapeutic Target for Nasopharyngeal Carcinoma Metastasis

Distant metastasis is a major cause of treatment failure in nasopharyngeal carcinoma (NPC) patients. Cell surface proteins represent attractive targets for cancer diagnosis or therapy. However, the cell surface proteins associated with NPC metastasis are poorly understood. To identify potential ther...

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Bibliographic Details
Main Authors: Maoyu Li, Fang Peng, Guoqiang Wang, Xujun Liang, Meiying Shao, Zhuchu Chen, Yongheng Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
nasopharyngeal carcinoma
cell surface proteins
metastasis
biotinylation
SILAC
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.621810/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.621810/full

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