EPIGENE: genome-wide transcription unit annotation using a multivariate probabilistic model of histone modifications

EPIGENE: genome-wide transcription unit annotation using a multivariate probabilistic model of histone modifications

Abstract Background Understanding the transcriptome is critical for explaining the functional as well as regulatory roles of genomic regions. Current methods for the identification of transcription units (TUs) use RNA-seq that, however, require large quantities of mRNA rendering the identification o...

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Bibliographic Details
Main Authors: Anshupa Sahu, Na Li, Ilona Dunkel, Ho-Ryun Chung
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Epigenetics & Chromatin
Subjects:
Transcription
Epigenetics
Histone modifications
Hidden Markov model
Transcript identification
Online Access:http://link.springer.com/article/10.1186/s13072-020-00341-z

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http://link.springer.com/article/10.1186/s13072-020-00341-z

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