Extracellular Microvesicles from Astrocytes Contain Functional Glutamate Transporters: Regulation by Protein Kinase C and Cell Activation

Extracellular Microvesicles from Astrocytes Contain Functional Glutamate Transporters: Regulation by Protein Kinase C and Cell Activation

Glutamate transport through astrocytic excitatory amino-acid transporters (EAAT)-1 and EAAT-2 is paramount for neural homeostasis. EAAT-1 has been reported in secreted extracellular microvesicles (eMV, such as exosomes) and because the Protein Kinase C (PKC) family controls the sub-cellular distribu...

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Bibliographic Details
Main Authors: Romain-Daniel eGosselin, Patrick eMeylan, Isabelle eDecosterd
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Protein Kinase C
Spinal Cord
glia
astrocyte
Nerve injury
glutamate transporters
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00251/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00251/full

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