Deletion of the α-(1,3)-glucan synthase genes induces a restructuring of the conidial cell wall responsible for the avirulence of Aspergillus fumigatus.

Deletion of the α-(1,3)-glucan synthase genes induces a restructuring of the conidial cell wall responsible for the avirulence of Aspergillus fumigatus.

α-(1,3)-Glucan is a major component of the cell wall of Aspergillus fumigatus, an opportunistic human fungal pathogen. There are three genes (AGS1, AGS2 and AGS3) controlling the biosynthesis of α-(1,3)-glucan in this fungal species. Deletion of all the three AGS genes resulted in a triple mutant th...

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Bibliographic Details
Main Authors: Anne Beauvais, Silvia Bozza, Olaf Kniemeyer, Cécile Formosa, Viviane Balloy, Christine Henry, Robert W Roberson, Etienne Dague, Michel Chignard, Axel A Brakhage, Luigina Romani, Jean-Paul Latgé
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3828178?pdf=render

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http://europepmc.org/articles/PMC3828178?pdf=render

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