Butyrate suppresses motility of colorectal cancer cells via deactivating Akt/ERK signaling in histone deacetylase dependent manner

Butyrate is a typical short chain fatty acid produced by gut microbiota of which the dysmetabolism has been consistently associated with colorectal diseases. However, whether butyrate affects metastatic colorectal cancer is not clear. In this study we investigated in vitro the effect of butyrate on...

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Bibliographic Details
Main Authors: Qingran Li, Chujie Ding, Tuo Meng, Wenjie Lu, Wenyue Liu, Haiping Hao, Lijuan Cao
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Journal of Pharmacological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861317301895