Elevated Klotho promoter methylation is associated with severity of chronic kidney disease.

Elevated Klotho promoter methylation is associated with severity of chronic kidney disease.

Klotho (KL) expression is down-regulated in the renal tissues of chronic kidney disease (CKD) animal models and patients with end-stage renal disease. The putative role of KL promoter hypermethylation in the progression of CKD remains unclear. The present study aimed to determine renal and periphera...

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Bibliographic Details
Main Authors: Jing Chen, Xiaoyan Zhang, Han Zhang, Jing Lin, Chen Zhang, Qing Wu, Xiaoqiang Ding
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3818221?pdf=render

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http://europepmc.org/articles/PMC3818221?pdf=render

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