DHX29 functions as an RNA co-sensor for MDA5-mediated EMCV-specific antiviral immunity.

DHX29 functions as an RNA co-sensor for MDA5-mediated EMCV-specific antiviral immunity.

Melanoma differentiation-associated gene-5 (MDA5) recognizes distinct subsets of viruses including Encephalomyocarditis virus (EMCV) of picornavirus family, but the molecular mechanisms underlying the specificity of the viral recognition of MDA5 in immune cells remain obscure. DHX29 is an RNA helica...

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Bibliographic Details
Main Authors: Qingyuan Zhu, Peng Tan, Yinyin Li, Meng Lin, Chaoran Li, Jingrong Mao, Jun Cui, Wei Zhao, Helen Y Wang, Rong-Fu Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5834211?pdf=render

Internet

http://europepmc.org/articles/PMC5834211?pdf=render

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