Endoplasmic reticulum stress and inflammation in the central nervous system

Abstract Persistent endoplasmic reticulum (ER) stress is thought to drive the pathology of many chronic disorders due to its potential to elicit aberrant inflammatory signaling and facilitate cell death. In neurodegenerative diseases, the accumulation of misfolded proteins and concomitant induction...

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Bibliographic Details
Main Authors: Neil T. Sprenkle, Savannah G. Sims, Cristina L. Sánchez, Gordon P. Meares
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Molecular Neurodegeneration
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13024-017-0183-y