Endoplasmic reticulum stress and inflammation in the central nervous system
Abstract Persistent endoplasmic reticulum (ER) stress is thought to drive the pathology of many chronic disorders due to its potential to elicit aberrant inflammatory signaling and facilitate cell death. In neurodegenerative diseases, the accumulation of misfolded proteins and concomitant induction...
Main Authors: | Neil T. Sprenkle, Savannah G. Sims, Cristina L. Sánchez, Gordon P. Meares |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-05-01
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Series: | Molecular Neurodegeneration |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13024-017-0183-y |
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