Kainic Acid-Induced Neurodegenerative Model: Potentials and Limitations

Excitotoxicity is considered to be an important mechanism involved in various neurodegenerative diseases in the central nervous system (CNS) such as Alzheimer's disease (AD). However, the mechanism by which excitotoxicity is implicated in neurodegenerative disorders remains unclear. Kainic acid...

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Bibliographic Details
Main Authors: Xiang-Yu Zheng, Hong-Liang Zhang, Qi Luo, Jie Zhu
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2011/457079