From disease association to risk assessment: an optimistic view from genome-wide association studies on type 1 diabetes.

From disease association to risk assessment: an optimistic view from genome-wide association studies on type 1 diabetes.

Genome-wide association studies (GWAS) have been fruitful in identifying disease susceptibility loci for common and complex diseases. A remaining question is whether we can quantify individual disease risk based on genotype data, in order to facilitate personalized prevention and treatment for compl...

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Main Authors: Zhi Wei, Kai Wang, Hui-Qi Qu, Haitao Zhang, Jonathan Bradfield, Cecilia Kim, Edward Frackleton, Cuiping Hou, Joseph T Glessner, Rosetta Chiavacci, Charles Stanley, Dimitri Monos, Struan F A Grant, Constantin Polychronakos, Hakon Hakonarson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2748686?pdf=render

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