Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans

Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans

Abstract Background End-stage kidney disease (ESKD) is a significant public health concern disproportionately affecting African Americans (AAs). Type 2 diabetes (T2D) is the leading cause of ESKD in the USA, and efforts to uncover genetic susceptibility to diabetic kidney disease (DKD) have had limi...

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Bibliographic Details
Main Authors: Meijian Guan, Jacob M. Keaton, Latchezar Dimitrov, Pamela J. Hicks, Jianzhao Xu, Nicholette D. Palmer, Lijun Ma, Swapan K. Das, Yii-Der I. Chen, Josef Coresh, Myriam Fornage, Nora Franceschini, Holly Kramer, Carl D. Langefeld, Josyf C. Mychaleckyj, Rulan S. Parekh, Wendy S. Post, Laura J. Rasmussen-Torvik, Stephen S. Rich, Jerome I. Rotter, John R. Sedor, Denyse Thornley-Brown, Adrienne Tin, James G. Wilson, Barry I. Freedman, Donald W. Bowden, Maggie C. Y. Ng, FIND Consortium
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Human Genomics
Subjects:
African Americans
Genome-wide association study
Type 2 diabetes
Diabetic kidney disease
End-stage kidney disease
Online Access:http://link.springer.com/article/10.1186/s40246-019-0205-7

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http://link.springer.com/article/10.1186/s40246-019-0205-7

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